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PGA3 pepsinogen 3, group I (pepsinogen A) [ Gallus gallus (chicken) ]

Gene ID: 395926, updated on 17-Aug-2024

Summary

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Symbol
PGA3provided by CGNC
Full Name
pepsinogen 3, group I (pepsinogen A)provided by CGNC
Primary source
CGNC:49555
See related
Ensembl:ENSGALG00010027352
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

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See PGA3 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (1469459..1472591)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (1440218..1443350)

Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112530323 Neighboring gene solute carrier family 16 member 4 Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 Neighboring gene prokineticin 1 Neighboring gene potassium voltage-gated channel subfamily A member 10 Neighboring gene potassium voltage-gated channel subfamily A member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of transcription regulatory regions of embryonic chicken pepsinogen (ECPg) gene. Watanuki K, et al. Dev Dyn, 2003 Sep. PMID 12950079
  2. Molecular cloning and the nucleotide sequence of cDNA for embryonic chicken pepsinogen: phylogenetic relationship with prochymosin. Hayashi K, et al. J Biochem, 1988 Feb. PMID 3131317
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An analysis of the transcription regulatory regions of pepsinogen was made.
    Title: Analysis of transcription regulatory regions of embryonic chicken pepsinogen (ECPg) gene.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
embryonic pepsinogen
NP_990385.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205054.2 → NP_990385.1  embryonic pepsinogen precursor

    See identical proteins and their annotated locations for NP_990385.1

    Status: PROVISIONAL

    Source sequence(s)
    D00215
    UniProtKB/Swiss-Prot
    P16476
    UniProtKB/TrEMBL
    A0A8V1ABH1
    Related
    ENSGALP00010040581.1, ENSGALT00010066315.1
    Conserved Domains (3) summary
    cd05478
    Location:66 → 381
    pepsin_A; Pepsin A, aspartic protease produced in gastric mucosa of mammals
    pfam00026
    Location:75 → 382
    Asp; Eukaryotic aspartyl protease
    pfam07966
    Location:17 → 45
    A1_Propeptide; A1 Propeptide

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1469459..1472591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1440218..1443350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P16476.1 GenPept UniProtKB/Swiss-Prot:P16476

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials