GABRA6 gamma-aminobutyric acid type A receptor alpha6 subunit [Gallus gallus (chicken)] - Gene

Summary

Symbol: GABRA6provided by CGNC
Full Name: gamma-aminobutyric acid type A receptor alpha6 subunitprovided by CGNC
Primary source: CGNC:1184
See related: Ensembl:ENSGALG00010009930
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (6894890..6920211, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (6904249..6930014, complement)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GABA-A receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables GABA-gated chloride ion channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables benzodiazepine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables inhibitory extracellular ligand-gated monoatomic ion channel activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chloride transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gamma-aminobutyric acid signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nervous system process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of postsynaptic membrane potential	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in synaptic transmission, GABAergic	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of GABA-A receptor complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in dendrite membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in neuron projection	IEA Inferred from Electronic Annotation more info	PubMed
located_in postsynapse	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: gamma-aminobutyric acid receptor subunit alpha-6

Names: GABA(A) receptor subunit alpha-6; GABA-A receptor a6 subunit; GABAAR subunit alpha-6; gamma-aminobutyric acid (GABA) A receptor, alpha 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205058.2 → NP_990389.1 gamma-aminobutyric acid receptor subunit alpha-6 precursor

See identical proteins and their annotated locations for NP_990389.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000256

UniProtKB/Swiss-Prot

Q90845

UniProtKB/TrEMBL

A0A8V0XZ57

Related

ENSGALP00010013580.1, ENSGALT00010023671.1

Conserved Domains (3) summary

TIGR00860
Location:34 → 442

LIC; Cation transporter family protein

pfam02931
Location:33 → 240

Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain

pfam02932
Location:247 → 439

Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

6894890..6920211 complement

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GenBank, FASTA, Sequence Viewer (Graphics)