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CG4914 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39597, updated on 9-Dec-2024

Summary

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Official Symbol
CG4914provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036436
Locus tag
Dmel_CG4914
See related
AllianceGenome:FB:FBgn0036436
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4914; SP39
Summary
Enables serine hydrolase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in several structures, including cuboidal/columnar epithelium; embryonic hindgut; embryonic precursor of adult hindgut; embryonic ventral epidermis; and foregut primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4914 in Genome Data Viewer
Location:
70E7-70E7; 3-42 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (14674538..14678147, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (14667638..14671247, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:initiator Methionine-CAT 1-4 Neighboring gene transfer RNA:initiator Methionine-CAT 1-5 Neighboring gene omega Neighboring gene Dynein axonemal assembly factor 6 Neighboring gene goddard

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription. Ni JQ, et al. Genes Dev, 2006 Jul 15. PMID 16816001, Free PMC Article
  2. Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes. Klebes A, et al. Development, 2005 Aug. PMID 16077094
  3. Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. Firth LC, et al. Dev Biol, 2007 Jul 15. PMID 17553483, Free PMC Article
  4. Trachealess (Trh) regulates all tracheal genes during Drosophila embryogenesis. Chung S, et al. Dev Biol, 2011 Dec 1. PMID 21963537, Free PMC Article
  5. Genome-wide analyses of Shavenbaby target genes reveals distinct features of enhancer organization. Menoret D, et al. Genome Biol, 2013 Aug 23. PMID 23972280, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine hydrolase activity HDA PubMed 
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4914-PA
NP_648711.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    14674538..14678147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140454.3 → NP_648711.1  uncharacterized protein Dmel_CG4914 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648711.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95R91, Q9VUG2
    Related
    FBpp0075456
    Conserved Domains (2) summary
    smart00020
    Location:127 → 360
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:128 → 363
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VUG2 Q9VUG2

Gene LinkOut

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