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SNAI1 snail family transcriptional repressor 1 [ Gallus gallus (chicken) ]

Gene ID: 396047, updated on 17-Aug-2024

Summary

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Symbol
SNAI1provided by CGNC
Full Name
snail family transcriptional repressor 1provided by CGNC
Primary source
CGNC:6068
See related
Ensembl:ENSGALG00010015071
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See SNAI1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
3
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (14133506..14136898, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (13919425..13922817, complement)

Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 189 Neighboring gene ubiquitin conjugating enzyme E2 V1 Neighboring gene uncharacterized LOC112530132 Neighboring gene ring finger protein 114 Neighboring gene spermatogenesis associated 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Snai1 is important for avian epicardial cell transformation and motility. Tao G, et al. Dev Dyn, 2013 Jun. PMID 23553854, Free PMC Article
  2. The timing of emergence of muscle progenitors is controlled by an FGF/ERK/SNAIL1 pathway. Delfini MC, et al. Dev Biol, 2009 Sep 15. PMID 19445915
  3. A right-sided pathway involving FGF8/Snai1 controls asymmetric development of the proepicardium in the chick embryo. Schlueter J, et al. Proc Natl Acad Sci U S A, 2009 May 5. PMID 19365073, Free PMC Article
  4. Expression of chicken slug and snail in mesenchymal components of the developing central nervous system. Marin F, et al. Dev Dyn, 2004 May. PMID 15108319
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Snai1 has multiple roles in regulating avian epicardial development
    Title: Snai1 is important for avian epicardial cell transformation and motility.
  2. the FGF/ERK/SNAIL1 pathway controls the timing of emergence of muscle progenitors
    Title: The timing of emergence of muscle progenitors is controlled by an FGF/ERK/SNAIL1 pathway.
  3. Experimental interference with the right-side determinants Fgf8 or Snai1 prevented proepicardium formation, whereas ectopic left-sided expression of Fgf8 or Snai1 resulted in bilateral proepicardium development.
    Title: A right-sided pathway involving FGF8/Snai1 controls asymmetric development of the proepicardium in the chick embryo.
  4. Slug is expressed in the meninges and in the pericytes/vascular smooth muscle cells of the brain, the spinal cord and other embryonic tissues; snail is expressed in the stroma of the choroid plexus of both the developmng hindbrain and the forebrain
    Title: Expression of chicken slug and snail in mesenchymal components of the developing central nervous system.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
zinc finger protein SNAI1
Names
snail homolog 1
snail like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205142.2 → NP_990473.1  zinc finger protein SNAI1

    See identical proteins and their annotated locations for NP_990473.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000328
    UniProtKB/TrEMBL
    O12939
    Related
    ENSGALP00010021085.1, ENSGALT00010036267.1
    Conserved Domains (4) summary
    COG5048
    Location:170 → 246
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:175 → 195
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:201 → 223
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:188 → 211
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14133506..14136898 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13919425..13922817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials