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MYL9 myosin, light chain 9, regulatory [ Gallus gallus (chicken) ]

Gene ID: 396215, updated on 3-Dec-2024

Summary

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Official Symbol
MYL9provided by CGNC
Official Full Name
myosin, light chain 9, regulatoryprovided by CGNC
Primary source
CGNC:49705
See related
Ensembl:ENSGALG00010021572
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
G1; DTNB; MLC2; MLC-2
Orthologs
human mouse all
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Genomic context

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See MYL9 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (795088..801859, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (445069..451835, complement)

Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene DLG associated protein 4 Neighboring gene TGFB induced factor homeobox 2 Neighboring gene chromosome 20 open reading frame, human C20orf24 Neighboring gene uncharacterized LOC121107322 Neighboring gene gamma-glutamyltransferase 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Amino-acid sequence of the 20 000-molecular-weight light chain of chicken gizzard-muscle myosin. Maita T, et al. Eur J Biochem, 1981 Jul. PMID 7274219
  2. Phosphorylation site sequence of smooth muscle myosin light chain (Mr = 20 000). Pearson RB, et al. FEBS Lett, 1984 Mar 12. PMID 6546724
  3. Molecular cloning and sequencing of the chicken smooth muscle myosin regulatory light chain. Messer NG, et al. FEBS Lett, 1988 Jul 4. PMID 3391271
  4. The nucleotide sequence of chicken smooth muscle myosin light chain two. Zavodny PJ, et al. Nucleic Acids Res, 1988 Feb 11. PMID 3344215, Free PMC Article
  5. Two distinct factor-binding DNA elements in cardiac myosin light chain 2 gene are essential for repression of its expression in skeletal muscle. Isolation of a cDNA clone for repressor protein Nished. Dhar M, et al. J Biol Chem, 1997 Jul 18. PMID 9218494

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Upstream regulatory sequences are identified and the authors show that CFDP1 binds the regulatory motif.
    Title: Two distinct factor-binding DNA elements in cardiac myosin light chain 2 gene are essential for repression of its expression in skeletal muscle. Isolation of a cDNA clone for repressor protein Nished.
  2. myosin light chain-2v is upregulated in cardiac hypertrophy by the complex of Nished and NFATc4, and co-activator p300 bound to an intronic regulatory element
    Title: A ternary complex of transcription factors, Nishéd and NFATc4, and co-activator p300 bound to an intronic sequence, intronic regulatory element, is pivotal for the up-regulation of myosin light chain-2v gene in cardiac hypertrophy.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in myofibril assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in platelet aggregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in myofibril IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myosin regulatory light chain 2, smooth muscle major isoform
Names
isoform L20-A
light polypeptide 9
myosin light chain 2
myosin regulatory light polypeptide 9
myosin, light polypeptide 9, regulatory

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205278.1 → NP_990609.1  myosin regulatory light chain 2, smooth muscle major isoform

    See identical proteins and their annotated locations for NP_990609.1

    Status: PROVISIONAL

    Source sequence(s)
    X06387
    UniProtKB/Swiss-Prot
    P02612
    UniProtKB/TrEMBL
    A0A8V0ZIV3
    Conserved Domains (1) summary
    COG5126
    Location:19 → 169
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    795088..801859 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015296241.4 → XP_015151727.1  myosin regulatory light chain 2, smooth muscle major isoform isoform X1

    UniProtKB/Swiss-Prot
    P02612
    UniProtKB/TrEMBL
    A0A8V0ZIV3
    Related
    ENSGALP00010031282.1, ENSGALT00010052353.1
    Conserved Domains (1) summary
    COG5126
    Location:19 → 169
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

  2. XM_015296240.4 → XP_015151726.1  myosin regulatory light chain 2, smooth muscle major isoform isoform X1

    UniProtKB/Swiss-Prot
    P02612
    UniProtKB/TrEMBL
    A0A8V0ZIV3
    Related
    ENSGALP00010031285.1, ENSGALT00010052357.1
    Conserved Domains (1) summary
    COG5126
    Location:19 → 169
    FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    445069..451835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046930601.1 → XP_046786557.1  myosin regulatory light chain 2, smooth muscle major isoform isoform X1

    UniProtKB/Swiss-Prot
    P02612
    UniProtKB/TrEMBL
    A0A8V0ZIV3

  2. XM_046930600.1 → XP_046786556.1  myosin regulatory light chain 2, smooth muscle major isoform isoform X1

    UniProtKB/Swiss-Prot
    P02612
    UniProtKB/TrEMBL
    A0A8V0ZIV3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02612.2 GenPept UniProtKB/Swiss-Prot:P02612

Gene LinkOut

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