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LMX1B LIM homeobox transcription factor 1 beta [ Gallus gallus (chicken) ]

Gene ID: 396312, updated on 3-Dec-2024

Summary

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Symbol
LMX1Bprovided by CGNC
Full Name
LIM homeobox transcription factor 1 betaprovided by CGNC
Primary source
CGNC:621
See related
Ensembl:ENSGALG00010028911
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
LMX; LMX1
Orthologs
human mouse all
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Genomic context

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See LMX1B in Genome Data Viewer
Location:
chromosome: 17
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 17 NC_052548.1 (10665426..10802338)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 17 NC_052589.1 (10076023..10212937)

Chromosome 17 - NC_052548.1Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein-like Neighboring gene ALC protein Neighboring gene uncharacterized LOC121107054 Neighboring gene uncharacterized LOC112529992 Neighboring gene zinc finger and BTB domain containing 43

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm. Mauch TJ, et al. Dev Biol, 2000 Apr 1. PMID 10720431
  2. Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Riddle RD, et al. Cell, 1995 Nov 17. PMID 7585966
  3. Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Vogel A, et al. Nature, 1995 Dec 14. PMID 7501017
  4. Characterization of migration behavior of myogenic precursor cells in the limb bud with respect to Lmx1b expression. Schweizer H, et al. Anat Embryol (Berl), 2004 Apr. PMID 15007643
  5. ALC (adjacent to LMX1 in chick) is a novel dorsal limb mesenchyme marker. Holmes G, et al. Gene Expr Patterns, 2003 Dec. PMID 14643681

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LIM/homeobox protein LMX-1.2
Names
LIM homeobox protein
LIM/homeobox protein 1
homeobox protein LMX-1
homeodomain protein (lmx)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205358.2 → NP_990689.2  LIM/homeobox protein LMX-1.2

    See identical proteins and their annotated locations for NP_990689.2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000308
    UniProtKB/Swiss-Prot
    P53413
    UniProtKB/TrEMBL
    A0A8V1AM41
    Related
    ENSGALP00010043070.1, ENSGALT00010069944.1
    Conserved Domains (3) summary
    cd09371
    Location:56 → 108
    LIM1_Lmx1b; The first LIM domain of Lmx1b
    cd09378
    Location:115 → 169
    LIM2_Lmx1a_Lmx1b; The second LIM domain of Lmx1a and Lmx1b
    pfam00046
    Location:221 → 275
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052548.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10665426..10802338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046901667.1 → XP_046757623.1  LIM/homeobox protein LMX-1.2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG34, A0A8V1AKC6
    Related
    ENSGALP00010043072.1, ENSGALT00010069946.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052589.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10076023..10212937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046928764.1 → XP_046784720.1  LIM/homeobox protein LMX-1.2 isoform X1

    UniProtKB/TrEMBL
    A0A8V1AG34, A0A8V1AKC6

  2. XM_046928765.1 → XP_046784721.1  LIM/homeobox protein LMX-1.2 isoform X2

    UniProtKB/TrEMBL
    A0A8V1AM41
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53413.2 GenPept UniProtKB/Swiss-Prot:P53413

Gene LinkOut

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Molecular Biology Databases
Research Materials