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TEC tec protein tyrosine kinase [ Gallus gallus (chicken) ]

Gene ID: 396407, updated on 3-Dec-2024

Summary

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Symbol
TECprovided by CGNC
Full Name
tec protein tyrosine kinaseprovided by CGNC
Primary source
CGNC:10536
See related
Ensembl:ENSGALG00010016851
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

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See TEC in Genome Data Viewer
Location:
chromosome: 4
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (66003396..66062398)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (65987512..66046454)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107053243 Neighboring gene solute carrier family 10 member 4 Neighboring gene SLAIN motif family member 2 Neighboring gene TXK tyrosine kinase Neighboring gene NIPA like domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of receptor tyrosine kinases in the embryonic chicken lens. Potts JD, et al. Curr Eye Res, 1993 Aug. PMID 8222737
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in T cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of platelet activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tissue regeneration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Tec
Names
protein kinase
NP_001025543.2
XP_015140906.1
XP_015140907.1
XP_015140908.1
XP_025005303.1
XP_046771544.1
XP_046771545.1
XP_046771546.1
XP_046771547.1
XP_046771548.1
XP_046771549.1
XP_046771550.1
XP_046771551.1
XP_046795891.1
XP_046795892.1
XP_046795893.1
XP_046795894.1
XP_046795895.1
XP_046795896.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030372.2 → NP_001025543.2  tyrosine-protein kinase Tec

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000074
    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88
    Related
    ENSGALP00010023627.1, ENSGALT00010040662.1
    Conserved Domains (4) summary
    cd10396
    Location:241 → 348
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11905
    Location:184 → 238
    SH3_Tec; Src Homology 3 domain of Tec (Tyrosine kinase expressed in hepatocellular carcinoma)
    cd01238
    Location:7 → 147
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
    cd05114
    Location:366 → 625
    PTKc_Tec_Rlk; Catalytic domain of the Protein Tyrosine Kinases, Tyrosine kinase expressed in hepatocellular carcinoma and Resting lymphocyte kinase

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    66003396..66062398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046939936.1 → XP_046795892.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88

  2. XM_046939937.1 → XP_046795893.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88

  3. XM_046939938.1 → XP_046795894.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88

  4. XM_046939939.1 → XP_046795895.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88

  5. XM_015285422.4 → XP_015140908.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88
    Conserved Domains (4) summary
    cd10396
    Location:241 → 348
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11905
    Location:184 → 238
    SH3_Tec; Src Homology 3 domain of Tec (Tyrosine kinase expressed in hepatocellular carcinoma)
    cd01238
    Location:7 → 147
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
    cd05114
    Location:366 → 625
    PTKc_Tec_Rlk; Catalytic domain of the Protein Tyrosine Kinases, Tyrosine kinase expressed in hepatocellular carcinoma and Resting lymphocyte kinase

  6. XM_015285421.4 → XP_015140907.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88
    Conserved Domains (4) summary
    cd10396
    Location:241 → 348
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11905
    Location:184 → 238
    SH3_Tec; Src Homology 3 domain of Tec (Tyrosine kinase expressed in hepatocellular carcinoma)
    cd01238
    Location:7 → 147
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
    cd05114
    Location:366 → 625
    PTKc_Tec_Rlk; Catalytic domain of the Protein Tyrosine Kinases, Tyrosine kinase expressed in hepatocellular carcinoma and Resting lymphocyte kinase

  7. XM_046939935.1 → XP_046795891.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88

  8. XM_015285420.3 → XP_015140906.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    F1NZY8, Q5ZI88
    Conserved Domains (4) summary
    cd10396
    Location:241 → 348
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11905
    Location:184 → 238
    SH3_Tec; Src Homology 3 domain of Tec (Tyrosine kinase expressed in hepatocellular carcinoma)
    cd01238
    Location:7 → 147
    PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
    cd05114
    Location:366 → 625
    PTKc_Tec_Rlk; Catalytic domain of the Protein Tyrosine Kinases, Tyrosine kinase expressed in hepatocellular carcinoma and Resting lymphocyte kinase

  9. XM_025149535.3 → XP_025005303.1  tyrosine-protein kinase Tec isoform X3

    UniProtKB/TrEMBL
    A0A8V0YXV4, Q5ZI88
    Related
    ENSGALP00010023621.1, ENSGALT00010040656.1
    Conserved Domains (4) summary
    cd10396
    Location:206 → 313
    SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
    cd11905
    Location:149 → 203
    SH3_Tec; Src Homology 3 domain of Tec (Tyrosine kinase expressed in hepatocellular carcinoma)
    cd05114
    Location:331 → 590
    PTKc_Tec_Rlk; Catalytic domain of the Protein Tyrosine Kinases, Tyrosine kinase expressed in hepatocellular carcinoma and Resting lymphocyte kinase
    cl17171
    Location:12 → 112
    PH-like; Pleckstrin homology-like domain

  10. XM_046939940.1 → XP_046795896.1  tyrosine-protein kinase Tec isoform X2

    UniProtKB/TrEMBL
    Q5ZI88

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    65987512..66046454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046915592.1 → XP_046771548.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    Q5ZI88

  2. XM_046915593.1 → XP_046771549.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    Q5ZI88

  3. XM_046915591.1 → XP_046771547.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    Q5ZI88

  4. XM_046915590.1 → XP_046771546.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    Q5ZI88

  5. XM_046915588.1 → XP_046771544.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    Q5ZI88

  6. XM_046915589.1 → XP_046771545.1  tyrosine-protein kinase Tec isoform X1

    UniProtKB/TrEMBL
    Q5ZI88

  7. XM_046915595.1 → XP_046771551.1  tyrosine-protein kinase Tec isoform X3

    UniProtKB/TrEMBL
    Q5ZI88

  8. XM_046915594.1 → XP_046771550.1  tyrosine-protein kinase Tec isoform X2

    UniProtKB/TrEMBL
    Q5ZI88
Nucleotide Protein Strain
Heading Accession and Version

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