KPNA1 karyopherin subunit alpha 1 [Sus scrofa (pig)] - Gene

Summary

Official Symbol: KPNA1provided by VGNC
Official Full Name: karyopherin subunit alpha 1provided by VGNC
Primary source: VGNC:VGNC:89560
See related: Ensembl:ENSSSCG00000028475
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Annotation information: Annotation category: partial on reference assembly
Expression: Ubiquitous expression in heart (RPKM 37.4), psoas major muscle (RPKM 36.6) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	13	NC_010455.5 (138045083..138100830)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	13	NC_010455.4 (147681201..147711773)

Chromosome 13 - NC_010455.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Nsp1beta inhibits interferon-activated STAT1/STAT2 signal transduction by inducing karyopherin-alpha1 degradation.
Title: Porcine reproductive and respiratory syndrome virus Nsp1β inhibits interferon-activated JAK/STAT signal transduction by inducing karyopherin-α1 degradation.

Submit: New GeneRIF Correction

General gene information

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Markers

Kpna1 (e-PCR), detects polymorphism
- UniSTS:143720

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables nuclear import signal receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear localization sequence binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in NLS-bearing protein import into nucleus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in postsynapse to nucleus signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: importin subunit alpha-5

Names: karyopherin alpha 1 (importin alpha 5)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.