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Taf4 - TBP-associated factor 4

Enables DNA binding activity; DNA-binding transcription factor binding activity; and TFIIA-class transcription factor complex binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in transcription initiation at RNA polymerase II promoter. Located in nucleus. Part of transcription factor TFIID complex. Is expressed in epithelial cell; epithelium; male accessory gland; seminal vesicle; and testis. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder and spermatogenic failure 13. Orthologous to several human genes including TAF4B (TATA-box binding protein associated factor 4b). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa