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ventx2.S VENT homeobox 2 gene 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397844, updated on 4-Jan-2025

Summary

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Official Symbol
ventx2.S
Official Full Name
VENT homeobox 2 gene 1 S homeolog
Primary source
Xenbase:XB-GENE-6252342
Locus tag
XELAEV_18036903mg
See related
EnsemblRapid:ENSXLAG00005012746 AllianceGenome:Xenbase:XB-GENE-6252342
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
vox; xom; vox1; Xbr-1a; xbr-1b; Xvr-11b; xvent-2; ventx2.1; xvent-2b; ventx2.1-a; ventx2.1-b; ventx2.1.S
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to act upstream of or within regulation of DNA-templated transcription and spinal cord motor neuron cell fate specification. Predicted to be located in nucleus. Is expressed in ectoderm; nervous system; pharyngeal arch; and respiratory system. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ventx2.S in Genome Data Viewer
Location:
chromosome: 7S
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (16926730..16928499, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (16932132..16933901, complement)

Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene VENT homeobox 2, gene 2 S homeolog Neighboring gene VENT homeobox 1 gene 1 S homeolog Neighboring gene adhesion G protein-coupled receptor A1 S homeolog Neighboring gene vertebrate ancient opsin S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox. Schmidt JE, et al. Development, 1996 Jun. PMID 8674411
  2. A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye. Papalopulu N, et al. Dev Biol, 1996 Feb 25. PMID 8626010
  3. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Shen M, et al. Genes Dev, 1998 Mar 1. PMID 9499405, Free PMC Article
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within spinal cord motor neuron cell fate specification IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
VENT homeobox 2 gene 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087981.1 → NP_001081450.1  VENT homeobox 2 gene 1 S homeolog

    See identical proteins and their annotated locations for NP_001081450.1

    Status: PROVISIONAL

    Source sequence(s)
    U43938
    UniProtKB/TrEMBL
    Q91669, Q91877
    Related
    ENSXLAP00005037478.1, ENSXLAT00005038387.1
    Conserved Domains (1) summary
    pfam00046
    Location:187 → 239
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    16926730..16928499 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials