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CG7724 - uncharacterized protein

Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and steroid delta-isomerase activity. Predicted to be involved in steroid biosynthetic process. Is expressed in several structures, including adult head; clypeo-labral primordium; embryonic dorsal epidermis; embryonic epipharynx; and embryonic head epidermis. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 1; hypertension; hypospadias; and intrahepatic cholestasis. Orthologous to several human genes including HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

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Species Gene Architecture aa