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tap - target of Poxn

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Involved in axon guidance; mushroom body development; and negative regulation of axon extension involved in axon guidance. Located in nucleus. Is expressed in several structures, including anlage in statu nascendi; ganglia; head epidermis primordium; presumptive embryonic/larval system; and somatic precursor cell. Human ortholog(s) of this gene implicated in congenital malabsorptive diarrhea 4; glucose intolerance; and type 2 diabetes mellitus. Orthologous to human NEUROG1 (neurogenin 1); NEUROG2 (neurogenin 2); and NEUROG3 (neurogenin 3). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa