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Cdin1 CDAN1 interacting nuclease 1 [ Mus musculus (house mouse) ]

Gene ID: 399568, updated on 27-Nov-2024

Summary

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Official Symbol
Cdin1provided by MGI
Official Full Name
CDAN1 interacting nuclease 1provided by MGI
Primary source
MGI:MGI:3026886
See related
Ensembl:ENSMUSG00000040282 AllianceGenome:MGI:3026886
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be involved in erythrocyte differentiation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; retina; submandibular gland primordium; and thymus primordium. Human ortholog(s) of this gene implicated in congenital dyserythropoietic anemia type Ib. Orthologous to human CDIN1 (CDAN1 interacting nuclease 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 3.0), CNS E18 (RPKM 2.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Cdin1 in Genome Data Viewer
Location:
2 E4; 2 58.18 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (115411388..115609263)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (115580907..115778774)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 3110099E03 gene Neighboring gene STARR-seq mESC enhancer starr_05416 Neighboring gene predicted gene, 39911 Neighboring gene STARR-seq mESC enhancer starr_05417 Neighboring gene microRNA 1951 Neighboring gene STARR-seq mESC enhancer starr_05421 Neighboring gene STARR-seq mESC enhancer starr_05422 Neighboring gene predicted gene, 52524 Neighboring gene predicted gene, 31590 Neighboring gene Meis homeobox 2 Neighboring gene STARR-seq mESC enhancer starr_05429 Neighboring gene STARR-seq mESC enhancer starr_05430 Neighboring gene RIKEN cDNA G630016G05 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Lawson KA, et al. Nature, 2020 Oct. PMID 32968282, Free PMC Article
  2. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
  3. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  4. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC62402

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in erythrocyte differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
  
involved_in erythrocyte differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
CDAN1-interacting nuclease 1
Names
protein C15orf41 homolog
uncharacterized protein C15orf41 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145898.2 → NP_001139370.1  CDAN1-interacting nuclease 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037
    Consensus CDS
    CCDS50662.1
    UniProtKB/TrEMBL
    E9PWV4
    Related
    ENSMUSP00000126772.2, ENSMUST00000166472.8
    Conserved Domains (1) summary
    pfam14811
    Location:135 → 271
    TPD; Protein of unknown function TPD sequence-motif

  2. NM_001409759.1 → NP_001396688.1  CDAN1-interacting nuclease 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  3. NM_001409760.1 → NP_001396689.1  CDAN1-interacting nuclease 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  4. NM_001409761.1 → NP_001396690.1  CDAN1-interacting nuclease 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  5. NM_001409762.1 → NP_001396691.1  CDAN1-interacting nuclease 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  6. NM_001409763.1 → NP_001396692.1  CDAN1-interacting nuclease 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  7. NM_001409764.1 → NP_001396693.1  CDAN1-interacting nuclease 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  8. NM_001409765.1 → NP_001396694.1  CDAN1-interacting nuclease 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  9. NM_001409766.1 → NP_001396695.1  CDAN1-interacting nuclease 1 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037

  10. NM_207264.5 → NP_997147.3  CDAN1-interacting nuclease 1 isoform 2

    See identical proteins and their annotated locations for NP_997147.3

    Status: VALIDATED

    Source sequence(s)
    AL844544, AL844901, AL929037
    Consensus CDS
    CCDS50663.1
    UniProtKB/Swiss-Prot
    Q3U4G0, Q80WT3, Q8C1X6
    Related
    ENSMUSP00000106543.3, ENSMUST00000110918.3
    Conserved Domains (1) summary
    pfam14811
    Location:132 → 269
    TPD; Protein of unknown function TPD sequence-motif

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    115411388..115609263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162351.1 → XP_036018244.1  CDAN1-interacting nuclease 1 isoform X3

    Conserved Domains (1) summary
    pfam14811
    Location:119 → 235
    TPD; Protein of unknown function TPD sequence-motif

  2. XM_017319079.2 → XP_017174568.1  CDAN1-interacting nuclease 1 isoform X4

    Conserved Domains (1) summary
    pfam14811
    Location:122 → 229
    TPD; Protein of unknown function TPD sequence-motif

  3. XM_036162350.1 → XP_036018243.1  CDAN1-interacting nuclease 1 isoform X1

    Conserved Domains (1) summary
    pfam14811
    Location:132 → 248
    TPD; Protein of unknown function TPD sequence-motif

  4. XM_036162353.1 → XP_036018246.1  CDAN1-interacting nuclease 1 isoform X5

    Conserved Domains (1) summary
    pfam14811
    Location:132 → 248
    TPD; Protein of unknown function TPD sequence-motif

  5. XM_036162354.1 → XP_036018247.1  CDAN1-interacting nuclease 1 isoform X6

    Conserved Domains (1) summary
    pfam14811
    Location:132 → 248
    TPD; Protein of unknown function TPD sequence-motif

  6. XM_036162352.1 → XP_036018245.1  CDAN1-interacting nuclease 1 isoform X3

    Conserved Domains (1) summary
    pfam14811
    Location:119 → 235
    TPD; Protein of unknown function TPD sequence-motif
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3U4G0.2 GenPept UniProtKB/Swiss-Prot:Q3U4G0

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