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Nedd4 - Nedd4

Enables several functions, including Notch binding activity; myosin binding activity; and ubiquitin protein ligase activity. Involved in several processes, including imaginal disc-derived wing vein morphogenesis; negative regulation of signal transduction; and positive regulation of cellular component organization. Located in plasma membrane and subsynaptic reticulum. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to several human genes including NEDD4L (NEDD4 like E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa