U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tdpoz5 TD and POZ domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 399676, updated on 4-Jan-2025

Summary

Official Symbol
Tdpoz5provided by MGI
Official Full Name
TD and POZ domain containing 5provided by MGI
Primary source
MGI:MGI:3027905
See related
Ensembl:ENSMUSG00000094163 AllianceGenome:MGI:3027905
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of proteolysis. Predicted to be active in cytoplasm and nucleus. Is expressed in early conceptus; secondary oocyte; and testis. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tdpoz5 in Genome Data Viewer
Location:
3 F2.1; 3 40.51 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (93867599..93868621, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (93960292..93961314, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene TD and POZ domain containing pseudogene Neighboring gene STARR-seq mESC enhancer starr_08337 Neighboring gene STARR-seq mESC enhancer starr_08338 Neighboring gene TD and POZ domain containing 9, pseudogene 1 Neighboring gene TD and POZ domain containing pseudogene Neighboring gene predicted pseudogene 9124

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
TD and POZ domain-containing protein 5
Names
TD and POZ domain containing gene 5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207273.2NP_997156.2  TD and POZ domain-containing protein 5

    See identical proteins and their annotated locations for NP_997156.2

    Status: VALIDATED

    Source sequence(s)
    AC170911, BC111104
    Consensus CDS
    CCDS17588.1
    UniProtKB/Swiss-Prot
    Q6YCH1
    UniProtKB/TrEMBL
    E0CYU8, E9QLP9, Q2NL42
    Related
    ENSMUSP00000096478.2, ENSMUST00000098879.2
    Conserved Domains (4) summary
    smart00225
    Location:189287
    BTB; Broad-Complex, Tramtrack and Bric a brac
    cd14734
    Location:287339
    SPOP_C; BACK-like Domain C-terminal to BTB in speckle-type POZ protein (SPOP) and similar proteins
    pfam00651
    Location:178284
    BTB; BTB/POZ domain
    cl02446
    Location:16153
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    93867599..93868621 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)