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CG42816 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39977, updated on 4-Jan-2025

Summary

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Official Symbol
CG42816provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0261998
Locus tag
Dmel_CG42816
See related
AllianceGenome:FB:FBgn0261998
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32186; CG5587; CG5944; DmCG32186; Dmel\CG42816
Old locus tag
Dmel_CG32186
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in gastric adenocarcinoma. Orthologous to human ABCA13 (ATP binding cassette subfamily A member 13). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG42816 in Genome Data Viewer
Location:
75A2-75A2; 3-45 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17792088..17797594, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17785188..17790694, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44668 Neighboring gene uncharacterized protein Neighboring gene Nucleobindin 1 Neighboring gene aramis

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATP-Binding Cassette (ABC) Transporter Genes Involved in Pyrethroid Resistance in the Malaria Vector Anopheles sinensis: Genome-Wide Identification, Characteristics, Phylogenetics, and Expression Profile. He Q, et al. Int J Mol Sci, 2019 Mar 20. PMID 30897799, Free PMC Article
  2. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Ren Q, et al. Nucleic Acids Res, 2007 Jan. PMID 17135193, Free PMC Article
  3. The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance. Dermauw W, et al. Insect Biochem Mol Biol, 2014 Feb. PMID 24291285
  4. The human ATP-binding cassette (ABC) transporter superfamily. Dean M, et al. Genome Res, 2001 Jul. PMID 11435397
  5. Genome-wide view of cell fate specification: ladybird acts at multiple levels during diversification of muscle and heart precursors. Junion G, et al. Genes Dev, 2007 Dec 1. PMID 18056427, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables lipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in lipid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG42816-PB
NP_730301.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17792088..17797594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168748.4 → NP_730301.3  uncharacterized protein Dmel_CG42816 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730301.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVK6
    Conserved Domains (3) summary
    cd03263
    Location:339 → 556
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:336 → 643
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:821 → 1018
    ABC2_membrane_3; ABC-2 family transporter protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VVK6 Q9VVK6

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