Ir75a Ionotropic receptor 75a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Ir75aprovided by FlyBase
Official Full Name: Ionotropic receptor 75aprovided by FlyBase
Primary source: FLYBASE:FBgn0036757
Locus tag: Dmel_CG14585
See related: AllianceGenome:FB:FBgn0036757
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 75a; CG14585; DmelIR75a; Dmel\CG14585; DmIr75a; IR75a; Ir75abc; IR75abc
Summary: Contributes to extracellular ligand-gated monoatomic ion channel activity and olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell and sensory perception of sound. Located in cell body; plasma membrane; and sensory dendrite. Is expressed in adult olfactory receptor neuron Ir75a; antennal coeloconic sensillum ac2; antennal coeloconic sensillum ac3; and antennal lobe glomerulus DP1l. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (17815570..17817921, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (17808670..17811021, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity.
Title: Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to extracellular ligand-gated monoatomic ion channel activity	IDA Inferred from Direct Assay more info	PubMed
enables ligand-gated monoatomic ion channel activity	IEA Inferred from Electronic Annotation more info
enables ligand-gated monoatomic ion channel activity	ISM Inferred from Sequence Model more info	PubMed
contributes_to olfactory receptor activity	IDA Inferred from Direct Assay more info	PubMed
enables olfactory receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in detection of chemical stimulus involved in sensory perception	IEP Inferred from Expression Pattern more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IDA Inferred from Direct Assay more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sensory perception of sound	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cell body	IDA Inferred from Direct Assay more info	PubMed
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	ISM Inferred from Sequence Model more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in sensory dendrite	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain