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ftz-f1 - ftz transcription factor 1

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including instar larval or pupal development; juvenile hormone mediated signaling pathway; and nervous system development. Located in nucleus. Is expressed in several structures, including appendage; follicle cell; gland; gut section; and ring gland. Human ortholog(s) of this gene implicated in 46,XX sex reversal 4; 46,XY sex reversal 3; Zellweger syndrome; primary ovarian insufficiency 7; and spermatogenic failure 8. Orthologous to several human genes including NR5A2 (nuclear receptor subfamily 5 group A member 2). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to ftz-f1

NCBI Orthologs

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Species Gene Architecture aa