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CG6843 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40062, updated on 9-Dec-2024

Summary

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Official Symbol
CG6843provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036827
Locus tag
Dmel_CG6843
See related
AllianceGenome:FB:FBgn0036827
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6843
Summary
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human CIR1 (corepressor interacting with RBPJ, CIR1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG6843 in Genome Data Viewer
Location:
75E4-75E4; 3-45 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18901594..18902952)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18894694..18896052)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L26 Neighboring gene asterix Neighboring gene COP9 signalosome subunit 1b Neighboring gene pre-mRNA processing factor 6 Neighboring gene Cytochrome c oxidase subunit 6A-like 2 Neighboring gene Ionotropic receptor 75d

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sox21b underlies the rapid diversification of a novel male genital structure between Drosophila species. Ridgway AM, et al. Curr Biol, 2024 Mar 11. PMID 38309269
  2. DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary. Ohtani H, et al. Genes Dev, 2013 Aug 1. PMID 23913921, Free PMC Article
  3. Drosophila melanogaster: A Valuable Genetic Model Organism to Elucidate the Biology of Retinitis Pigmentosa. Lehmann M, et al. Methods Mol Biol, 2019. PMID 30324448
  4. A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection. Glittenberg MT, et al. Dis Model Mech, 2022 May 1. PMID 35142345, Free PMC Article
  5. Systems genetics of complex traits in Drosophila melanogaster. Ayroles JF, et al. Nat Genet, 2009 Mar. PMID 19234471, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6843-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    18901594..18902952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140815.3 → NP_649072.1  uncharacterized protein Dmel_CG6843 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649072.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVU4
    Related
    FBpp0074834
    Conserved Domains (1) summary
    pfam10197
    Location:13 → 49
    Cir_N; N-terminal domain of CBF1 interacting co-repressor CIR
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MSD2 Q8MSD2
Q9VVU4 Q9VVU4

Gene LinkOut

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