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Ugt316A1 UDP-glycosyltransferase family 316 member A1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40079, updated on 9-Dec-2024

Summary

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Official Symbol
Ugt316A1provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 316 member A1provided by FlyBase
Primary source
FLYBASE:FBgn0036842
Locus tag
Dmel_CG3797
See related
AllianceGenome:FB:FBgn0036842
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG3797; Dmel\CG3797; UGT316A1
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Ugt316A1 in Genome Data Viewer
Location:
75F6-75F6; 3-45 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19059400..19062816, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19052500..19055916, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44675 Neighboring gene uncharacterized protein Neighboring gene Sideroflexin 2 Neighboring gene Mitogen-activated protein kinase phosphatase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of the feedback antagonist naked cuticle by Wingless signaling. Chang JL, et al. Dev Biol, 2008 Sep 15. PMID 18585374, Free PMC Article
  2. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
  3. Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP-glycosyltransferase gene. Luque T, et al. Insect Biochem Mol Biol, 2002 Dec. PMID 12429111
  4. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Halfon MS, et al. Genome Res, 2002 Jul. PMID 12097338, Free PMC Article
  5. Comparative analysis of the UDP-glycosyltransferase multigene family in insects. Ahn SJ, et al. Insect Biochem Mol Biol, 2012 Feb. PMID 22155036

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
UDP-glycosyltransferase family 316 member A1
Names
CG3797-PA
CG3797-PB
Ugt316A1-PA
Ugt316A1-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19059400..19062816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300182.1 → NP_001287111.1  UDP-glycosyltransferase family 316 member A1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287111.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVW2
    Conserved Domains (2) summary
    PHA03392
    Location:1 → 480
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    TIGR01426
    Location:39 → 448
    MGT; glycosyltransferase, MGT family

  2. NM_140828.3 → NP_649085.1  UDP-glycosyltransferase family 316 member A1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649085.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VVW2
    Related
    FBpp0074804
    Conserved Domains (2) summary
    PHA03392
    Location:1 → 480
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    TIGR01426
    Location:39 → 448
    MGT; glycosyltransferase, MGT family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VVW2 Q9VVW2

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