rept - reptin

Enables transcription corepressor activity. Involved in several processes, including autophagic cell death; chromatin remodeling; and negative regulation of canonical Wnt signaling pathway. Located in nucleus. Part of Ino80 complex; NuA4 histone acetyltransferase complex; and R2TP complex. Is expressed in several structures, including embryonic/larval midgut primordium; head epidermis primordium; mesoderm; sensory nervous system primordium; and visceral mesoderm derivative. Orthologous to human RUVBL2 (RuvB like AAA ATPase 2). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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