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CG9449 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40117, updated on 9-Dec-2024

Summary

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Official Symbol
CG9449provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036875
Locus tag
Dmel_CG9449
See related
AllianceGenome:FB:FBgn0036875
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG9449
Summary
Predicted to enable acid phosphatase activity. Predicted to be located in extracellular exosome and nucleus. Is expressed in amnioserosa; embryonic/larval salivary gland; and yolk nucleus. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Orthologous to human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG9449 in Genome Data Viewer
Location:
76B5-76B5; 3-45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19492053..19497723, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19485153..19490823, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene brivido-1 Neighboring gene hairpin RNA:CR33940 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Quantitative evolutionary genomics: differential gene expression and male reproductive success in Drosophila melanogaster. Drnevich JM, et al. Proc Biol Sci, 2004 Nov 7. PMID 15539352, Free PMC Article
  2. Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. Sieber MH, et al. Curr Biol, 2015 Apr 20. PMID 25802149, Free PMC Article
  3. The Hippo pathway promotes cell survival in response to chemical stress. Di Cara F, et al. Cell Death Differ, 2015 Sep. PMID 26021298, Free PMC Article
  4. A genomic response to the yeast transcription factor GAL4 in Drosophila. Liu Y, et al. Fly (Austin), 2008 Mar-Apr. PMID 18820459, Free PMC Article
  5. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables acid phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9449-PE
CG9449-PF
CG9449-PG
CG9449-PH
CG9449-PJ
CG9449-PK
NP_001137975.1
NP_001137976.1
NP_001262047.1
NP_001262048.1
NP_001262049.2
NP_001287119.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19492053..19497723 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275119.1 → NP_001262048.1  uncharacterized protein Dmel_CG9449, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262048.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z080
    Conserved Domains (1) summary
    cd07061
    Location:48 → 348
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

  2. NM_001275118.1 → NP_001262047.1  uncharacterized protein Dmel_CG9449, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262047.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z080
    Conserved Domains (1) summary
    cd07061
    Location:48 → 348
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

  3. NM_001144504.2 → NP_001137976.1  uncharacterized protein Dmel_CG9449, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137976.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z080
    Conserved Domains (1) summary
    cd07061
    Location:48 → 348
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

  4. NM_001275120.2 → NP_001262049.2  uncharacterized protein Dmel_CG9449, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262049.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCZ1
    Conserved Domains (1) summary
    cd07061
    Location:35 → 335
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

  5. NM_001144503.2 → NP_001137975.1  uncharacterized protein Dmel_CG9449, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137975.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z082
    Conserved Domains (1) summary
    cd07061
    Location:48 → 169
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction

  6. NM_001300190.1 → NP_001287119.1  uncharacterized protein Dmel_CG9449, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287119.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JBA7
    Conserved Domains (1) summary
    cd07061
    Location:35 → 156
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7Z080 B7Z080
B7Z082 B7Z082
M9PCZ1 M9PCZ1
Q8SY04 Q8SY04
X2JBA7 X2JBA7

Gene LinkOut

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