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CG14100 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40132, updated on 4-Jan-2025

Summary

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Official Symbol
CG14100provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036889
Locus tag
Dmel_CG14100
See related
AllianceGenome:FB:FBgn0036889
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14100
Summary
Predicted to enable rRNA (guanosine-2'-O-)-methyltransferase activity. Predicted to be involved in rRNA processing. Predicted to be active in mitochondrial matrix. Orthologous to human MRM3 (mitochondrial rRNA methyltransferase 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG14100 in Genome Data Viewer
Location:
76B8-76B8; 3-45 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19589072..19590524, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19582172..19583624, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Shaker cognate l Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene absent, small, or homeotic discs 1 Neighboring gene TBP-associated factor 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide analysis of Staufen-associated mRNAs identifies secondary structures that confer target specificity. Laver JD, et al. Nucleic Acids Res, 2013 Nov. PMID 23945942, Free PMC Article
  2. Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene. Kumar S, et al. Sci Rep, 2016 Nov 7. PMID 27819340, Free PMC Article
  3. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article
  4. A microtubule interactome: complexes with roles in cell cycle and mitosis. Hughes JR, et al. PLoS Biol, 2008 Apr 22. PMID 18433294, Free PMC Article
  5. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (guanosine-2'-O-)-methyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG14100-PA
NP_649130.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19589072..19590524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140873.4 → NP_649130.2  uncharacterized protein Dmel_CG14100 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649130.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SZ70, Q9VW14
    UniProtKB/TrEMBL
    H0RNK5
    Related
    FBpp0074739
    Conserved Domains (3) summary
    COG0566
    Location:131 → 399
    SpoU; tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]
    pfam00588
    Location:235 → 393
    SpoU_methylase; SpoU rRNA Methylase family
    pfam08032
    Location:141 → 214
    SpoU_sub_bind; RNA 2'-O ribose methyltransferase substrate binding
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VW14.1 Q9VW14

Gene LinkOut

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