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CG9372 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40137, updated on 4-Jan-2025

Summary

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Official Symbol
CG9372provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0036891
Locus tag
Dmel_CG9372
See related
AllianceGenome:FB:FBgn0036891
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
c-SP34; cSP34; Dmel\CG9372; SP34
Summary
Enables serine hydrolase activity. Involved in response to fungus. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic/larval posterior spiracle; posterior spiracle primordium; and sensory nervous system primordium. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG9372 in Genome Data Viewer
Location:
76B9-76B9; 3-45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19606208..19608368)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19599308..19601468)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene lush Neighboring gene Lon protease Neighboring gene lethal (3) 76BDm Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene anti-silencing factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Drosophila Hemolymph, Serine Proteases Are the Major Gelatinases and Caseinases. Gatti JL, et al. Insects, 2024 Mar 28. PMID 38667364, Free PMC Article
  2. Peptidomic and proteomic analyses of the systemic immune response of Drosophila. Levy F, et al. Biochimie, 2004 Sep-Oct. PMID 15556270
  3. Genetic evidence of a redox-dependent systemic wound response via Hayan protease-phenoloxidase system in Drosophila. Nam HJ, et al. EMBO J, 2012 Mar 7. PMID 22227521, Free PMC Article
  4. Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation. Veillard F, et al. Biochimie, 2016 Mar. PMID 26453810
  5. High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. Belozerov VE, et al. Mol Cell Biol, 2012 Sep. PMID 22801366, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables serine hydrolase activity HDA PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
involved_in proteolysis ISM
Inferred from Sequence Model
more info
 PubMed 
involved_in response to fungus HEP PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG9372-PA
NP_649132.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19606208..19608368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140875.3 → NP_649132.1  uncharacterized protein Dmel_CG9372 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649132.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VW19
    Related
    FBpp0074713
    Conserved Domains (3) summary
    smart00680
    Location:87 → 132
    CLIP; Clip or disulphide knot domain
    smart00020
    Location:173 → 402
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:176 → 402
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VW19 Q9VW19

Gene LinkOut

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