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PIG-F Phosphatidylinositol glycan anchor biosynthesis class F [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40139, updated on 9-Dec-2024

Summary

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Official Symbol
PIG-Fprovided by FlyBase
Official Full Name
Phosphatidylinositol glycan anchor biosynthesis class Fprovided by FlyBase
Primary source
FLYBASE:FBgn0036893
Locus tag
Dmel_CG9376
See related
AllianceGenome:FB:FBgn0036893
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9376; Dmel\CG9376; DmPIG-F
Summary
Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in adult head and organism. Orthologous to human PIGF (phosphatidylinositol glycan anchor biosynthesis class F). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See PIG-F in Genome Data Viewer
Location:
76B9-76B9; 3-45 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19612455..19613489)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19605555..19606589)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene lush Neighboring gene uncharacterized protein Neighboring gene Lon protease Neighboring gene lethal (3) 76BDm Neighboring gene anti-silencing factor 1 Neighboring gene male sterile (3) 76Cc

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila. Yamamoto-Hino M, et al. J Cell Sci, 2018 Oct 26. PMID 30266758, Free PMC Article
  2. A computational and experimental approach toward a priori identification of alternatively spliced exons. Philipps DL, et al. RNA, 2004 Dec. PMID 15525709, Free PMC Article
  3. Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. Kondylis V, et al. PLoS One, 2011 Feb 23. PMID 21383842, Free PMC Article
  4. Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep. Palermo J, et al. Sci Adv, 2023 Jan 6. PMID 36608130, Free PMC Article
  5. Heterochromatin protein 1 (HP1a) positively regulates euchromatic gene expression through RNA transcript association and interaction with hnRNPs in Drosophila. Piacentini L, et al. PLoS Genet, 2009 Oct. PMID 19798443, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
phosphatidylinositol glycan anchor biosynthesis class F
Names
CG9376-PA
PIG-F-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19612455..19613489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140877.4 → NP_649134.3  phosphatidylinositol glycan anchor biosynthesis class F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649134.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MTV3, Q9VW21
    Related
    FBpp0074714
    Conserved Domains (1) summary
    pfam06699
    Location:81 → 214
    PIG-F; GPI biosynthesis protein family Pig-F
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MTV3 Q8MTV3
Q9VW21 Q9VW21

Gene LinkOut

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