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Deaf1 - Deformed epidermal autoregulatory factor-1

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in embryo development; regulation of DNA-templated transcription; and regulation of immune response. Located in nucleus and polytene chromosome. Is expressed in several structures, including central brain primordium; embryonic/larval midgut; embryonic/larval midgut primordium; ganglia; and larval central nervous system. Human ortholog(s) of this gene implicated in Vulto-van Silfout-de Vries syndrome. Orthologous to human DEAF1 (DEAF1 transcription factor). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa