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Mi-2 - Mi-2

Enables ATP hydrolysis activity; chromatin binding activity; and nucleosome array spacer activity. Involved in several processes, including chromatin remodeling; chromosome organization; and negative regulation of transcription by RNA polymerase II. Located in euchromatin; nucleus; and polytene chromosome. Is expressed in several structures, including adult brain cell body rind; adult head; germline cell; gut section; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in Sifrim-Hitz-Weiss syndrome; colorectal cancer (multiple); lung cancer (multiple); and lymphoma. Orthologous to several human genes including CHD3 (chromodomain helicase DNA binding protein 3). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Mi-2

NCBI Orthologs

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Species Gene Architecture aa