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dcps decapping enzyme, scavenger [ Danio rerio (zebrafish) ]

Gene ID: 402850, updated on 4-Jan-2025

Summary

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Official Symbol
dcpsprovided by ZNC
Official Full Name
decapping enzyme, scavengerprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040311-1
See related
Ensembl:ENSDARG00000009862 AllianceGenome:ZFIN:ZDB-GENE-040311-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fa04d04; zgc:109723
Summary
Predicted to enable RNA 7-methylguanosine cap binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within mRNA processing. Predicted to be located in cytoplasm. Predicted to be active in P-body and nucleus. Orthologous to human DCPS (decapping enzyme, scavenger). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See dcps in Genome Data Viewer
Location:
chromosome: 10
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (39283999..39293639)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (39362512..39372152)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene FAD-dependent oxidoreductase domain containing 1 Neighboring gene cryptochrome circadian regulator 5 Neighboring gene kirre like nephrin family adhesion molecule 3a Neighboring gene potassium inwardly rectifying channel subfamily J member 1b Neighboring gene somatolactin beta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA 7-methylguanosine cap binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
m7GpppX diphosphatase
Names
histidine triad protein member 5
mRNA decapping enzyme
NP_991151.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205588.3 → NP_991151.3  m7GpppX diphosphatase

    Status: VALIDATED

    Source sequence(s)
    CU633782, EH547457
    UniProtKB/TrEMBL
    A0A8M1PGD6, F1R776
    Related
    ENSDARP00000022189.4, ENSDART00000016464.5
    Conserved Domains (1) summary
    cl27009
    Location:40 → 315
    DcpS; Scavenger mRNA decapping enzyme (DcpS) N-terminal

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    39283999..39293639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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