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CG4042 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40291, updated on 9-Dec-2024

Summary

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Official Symbol
CG4042provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037018
Locus tag
Dmel_CG4042
See related
AllianceGenome:FB:FBgn0037018
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
dATP5SL; Dmel\CG4042
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Is active in mitochondrion. Is expressed in several structures, including adult head; embryonic/larval midgut; embryonic/larval midgut primordium; and larval muscle cell. Orthologous to human DMAC2 (distal membrane arm assembly component 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4042 in Genome Data Viewer
Location:
77E6-77E6; 3-47 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20770143..20771507, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20763243..20764607, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pitslre Neighboring gene Peroxin 16 Neighboring gene Peroxin 14 Neighboring gene Phosphorylated CTD-interacting factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis. Murari A, et al. iScience, 2021 Aug 20. PMID 34386730, Free PMC Article
  2. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
  3. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
  4. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
  5. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitochondrial respiratory chain complex I assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG4042-PA
CG4042-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    20770143..20771507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275192.1 → NP_001262121.1  uncharacterized protein Dmel_CG4042, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262121.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYK3, Q9VPC1
    Conserved Domains (1) summary
    sd00034
    Location:192 → 221
    LRR_AMN1; leucine-rich repeat [structural motif]

  2. NM_140993.4 → NP_649250.2  uncharacterized protein Dmel_CG4042, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649250.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SYK3, Q9VPC1
    Related
    FBpp0077937
    Conserved Domains (1) summary
    sd00034
    Location:192 → 221
    LRR_AMN1; leucine-rich repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SYK3 Q8SYK3
Q9VPC1 Q9VPC1

Gene LinkOut

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