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sa spermatocyte arrest [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40367, updated on 4-Jan-2025

Summary

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Official Symbol
saprovided by FlyBase
Official Full Name
spermatocyte arrestprovided by FlyBase
Primary source
FLYBASE:FBgn0002842
Locus tag
Dmel_CG11308
See related
AllianceGenome:FB:FBgn0002842
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11308; Dmel\CG11308; dTAF8L; gfb; ms(3)sa; ms(3)VO45; ms(3)VO5; Sa; TAF-like; TAF8L; tTAF
Summary
Involved in male meiosis I; regulation of gene expression; and spermatid differentiation. Located in male germ cell nucleus and nucleolus. Is expressed in spermatid and spermatocyte. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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Location:
78D1-78D1; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21405425..21406738, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21398525..21399838, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene regeneration Neighboring gene long non-coding RNA:CR45953 Neighboring gene long non-coding RNA:CR45954 Neighboring gene barricade Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polycomb, trithorax and the decision to differentiate. Ringrose L. Bioessays, 2006 Apr. PMID 16547954
  2. Rapid male-specific regulatory divergence and down regulation of spermatogenesis genes in Drosophila species hybrids. Ferguson J, et al. PLoS One, 2013. PMID 23593487, Free PMC Article
  3. Monovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis. Gan Q, et al. Genome Biol, 2010. PMID 20398323, Free PMC Article
  4. The piRNA pathway is developmentally regulated during spermatogenesis in Drosophila. Quénerch'du E, et al. RNA, 2016 Jul. PMID 27208314, Free PMC Article
  5. A trans-activator on the Drosophila Y chromosome regulates gene expression in the male germ line. Zhang P, et al. Genetica, 2000. PMID 11293789

See all (84) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in male meiosis I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spermatid differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation at RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in male germ cell nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
spermatocyte arrest
Names
CG11308-PA
golfballs
sa-PA
spermatocytes arrest
testis-specific TBP associated factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21405425..21406738 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141054.3 → NP_649311.1  spermatocyte arrest [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649311.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QQ22, Q9VP40
    Related
    FBpp0078055
    Conserved Domains (2) summary
    cd08049
    Location:125 → 177
    TAF8; TATA Binding Protein (TBP) Associated Factor 8
    pfam07524
    Location:6 → 77
    Bromo_TP; Bromodomain associated
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VP40 Q9VP40

Gene LinkOut

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