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Syx6 Syntaxin 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40373, updated on 9-Dec-2024

Summary

Official Symbol
Syx6provided by FlyBase
Official Full Name
Syntaxin 6provided by FlyBase
Primary source
FLYBASE:FBgn0037084
Locus tag
Dmel_CG7736
See related
AllianceGenome:FB:FBgn0037084
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7736; CT23545; Dm Syx6; Dmel\CG7736; DmSyx6; SYN6; Syx; syx6; SYX6/10
Summary
Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in several processes, including retrograde transport, endosome to Golgi; synaptic vesicle docking; and vesicle fusion. Predicted to be located in plasma membrane. Predicted to be part of SNARE complex. Predicted to be active in synaptic vesicle membrane. Is expressed in embryonic brain; larval nervous system; larval ventral nerve cord; and organism. Orthologous to several human genes including STX10 (syntaxin 10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Syx6 in Genome Data Viewer
Location:
47D7-47E1; 2-64 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11219539..11222480)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7107044..7109985)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene schnurri Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene menage a trois Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables SNAP receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables SNAP receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Golgi vesicle transport IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in synaptic vesicle docking ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in vesicle docking IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in plasma membrane NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
syntaxin 6
Names
CG7736-PB
CG7736-PD
CG7736-PE
Syx6-PB
Syx6-PD
Syx6-PE
syntaxin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    11219539..11222480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_206093.3NP_995815.1  syntaxin 6, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995815.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86P32
    Conserved Domains (1) summary
    cd15851
    Location:137202
    SNARE_Syntaxin6; SNARE motif of syntaxin 6
  2. NM_206092.3NP_995814.1  syntaxin 6, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995814.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BI25, Q7JRF1
    Conserved Domains (2) summary
    cd15851
    Location:234299
    SNARE_Syntaxin6; SNARE motif of syntaxin 6
    cd21443
    Location:5103
    SNARE_NTD_STX6_STX10; N-terminal domain of syntaxin-6, syntaxin-10, and similar proteins
  3. NM_206094.3NP_995816.1  syntaxin 6, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995816.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5BI25, Q7JY00
    Conserved Domains (2) summary
    cd15851
    Location:250315
    SNARE_Syntaxin6; SNARE motif of syntaxin 6
    pfam09177
    Location:29115
    Syntaxin-6_N; Syntaxin 6, N-terminal