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CG7611 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40386, updated on 4-Jan-2025

Summary

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Official Symbol
CG7611provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037094
Locus tag
Dmel_CG7611
See related
AllianceGenome:FB:FBgn0037094
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7611; WDR26
Summary
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of GID complex. Is expressed in adult head and organism. Orthologous to human WDR26 (WD repeat domain 26). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG7611 in Genome Data Viewer
Location:
78D5-78D5; 3-47 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21523186..21528163)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21516286..21521263)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene M6 Neighboring gene Sak kinase Neighboring gene Cyclin-dependent kinase 12 Neighboring gene antisense RNA:CR43877 Neighboring gene ACAT-related protein required for viability 1 Neighboring gene Makorin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition. Zavortink M, et al. Elife, 2020 Jun 23. PMID 32573431, Free PMC Article
  2. mTORC1-chaperonin CCT signaling regulates m(6)A RNA methylation to suppress autophagy. Tang HW, et al. Proc Natl Acad Sci U S A, 2021 Mar 9. PMID 33649236, Free PMC Article
  3. dCas9-targeted locus-specific protein isolation method identifies histone gene regulators. Tsui C, et al. Proc Natl Acad Sci U S A, 2018 Mar 20. PMID 29507191, Free PMC Article
  4. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cao WX, et al. Cell Rep, 2020 Jun 23. PMID 32579915, Free PMC Article
  5. Proteomics approach to study the functions of Drosophila myosin VI through identification of multiple cargo-binding proteins. Finan D, et al. Proc Natl Acad Sci U S A, 2011 Apr 5. PMID 21368190, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of GID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GID complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7611-PA
CG7611-PB
CG7611-PC
CG7611-PD
CG7611-PE
CG7611-PG
CG7611-PH
CG7611-PI
CG7611-PJ

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21523186..21528163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170018.2 → NP_001163489.1  uncharacterized protein Dmel_CG7611, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163489.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_141069.4 → NP_649326.1  uncharacterized protein Dmel_CG7611, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649326.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078022
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. NM_168918.3 → NP_730649.1  uncharacterized protein Dmel_CG7611, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730649.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078017
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. NM_168913.3 → NP_730644.1  uncharacterized protein Dmel_CG7611, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730644.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078018
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. NM_168915.3 → NP_730646.1  uncharacterized protein Dmel_CG7611, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730646.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078021
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. NM_168914.3 → NP_730645.1  uncharacterized protein Dmel_CG7611, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730645.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078020
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  7. NM_168919.3 → NP_730650.1  uncharacterized protein Dmel_CG7611, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730650.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078019
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  8. NM_168917.3 → NP_730648.1  uncharacterized protein Dmel_CG7611, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730648.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0290416
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  9. NM_168916.3 → NP_730647.1  uncharacterized protein Dmel_CG7611, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730647.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V292, Q7K0L4
    UniProtKB/TrEMBL
    E1JHX5
    Related
    FBpp0078015
    Conserved Domains (4) summary
    smart00668
    Location:129 → 190
    CTLH; C-terminal to LisH motif
    COG2319
    Location:303 → 605
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:318 → 358
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:307 → 602
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JHX5 E1JHX5
Q7K0L4.1 Q7K0L4

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