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CG11247 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40414, updated on 9-Dec-2024

Summary

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Official Symbol
CG11247provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037120
Locus tag
Dmel_CG11247
See related
AllianceGenome:FB:FBgn0037120
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG11247
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; gut section; mesoderm; and sensory nervous system primordium. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG11247 in Genome Data Viewer
Location:
78E5-78E5; 3-47 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21724326..21728806, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21717426..21721906, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43978 Neighboring gene Seminal fluid protein 78E Neighboring gene uncharacterized protein Neighboring gene RNA polymerase II, I and III subunit H Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals. Doupé DP, et al. Proc Natl Acad Sci U S A, 2018 Nov 27. PMID 30404917, Free PMC Article
  2. Mes2, a MADF-containing transcription factor essential for Drosophila development. Zimmermann G, et al. Dev Dyn, 2006 Dec. PMID 17029287
  3. An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3'-end formation. Chen J, et al. RNA, 2012 Dec. PMID 23097424, Free PMC Article
  4. A protein network-guided screen for cell cycle regulators in Drosophila. Guest ST, et al. BMC Syst Biol, 2011 May 6. PMID 21548953, Free PMC Article
  5. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Stark A, et al. Cell, 2005 Dec 16. PMID 16337999

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG11247-PA
CG11247-PB
CG11247-PC
CG11247-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    21724326..21728806 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141094.5 → NP_649351.2  uncharacterized protein Dmel_CG11247, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649351.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9G3, Q9VNZ4
    Related
    FBpp0078113
    Conserved Domains (5) summary
    COG5048
    Location:88 → 247
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:295 → 315
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:238 → 260
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:165 → 189
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001104189.2 → NP_001097659.1  uncharacterized protein Dmel_CG11247, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097659.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9G3, Q9VNZ4
    Conserved Domains (5) summary
    COG5048
    Location:88 → 247
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:295 → 315
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:238 → 260
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:165 → 189
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001275260.1 → NP_001262189.1  uncharacterized protein Dmel_CG11247, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262189.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PD91
    Conserved Domains (4) summary
    COG5048
    Location:5 → 173
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:99 → 119
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:14 → 40
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:113 → 136
    zf-H2C2_2; Zinc-finger double domain

  4. NM_168936.3 → NP_730680.1  uncharacterized protein Dmel_CG11247, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730680.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9G3, Q9VNZ4
    Related
    FBpp0078112
    Conserved Domains (5) summary
    COG5048
    Location:88 → 247
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:295 → 315
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:238 → 260
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:165 → 189
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PD91 M9PD91
Q8T9G3 Q8T9G3
Q9VNZ4 Q9VNZ4

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