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ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [ Bos taurus (domestic cattle) ]

Gene ID: 404163, updated on 1-Jan-2025

Summary

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Official Symbol
ST3GAL4provided by VGNC
Official Full Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 4provided by VGNC
Primary source
VGNC:VGNC:35333
See related
Ensembl:ENSBTAG00000016506
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
SIAT4C; ST3GAL-IV
Orthologs
human mouse all
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Genomic context

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See ST3GAL4 in Genome Data Viewer
Location:
chromosome: 29
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (29698993..29739108)

Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene ferritin light chain-like Neighboring gene decapping enzyme, scavenger Neighboring gene kirre like nephrin family adhesion molecule 3 Neighboring gene uncharacterized LOC132344192 Neighboring gene uncharacterized LOC132344188

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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Related articles in PubMed

  1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycolipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4
Names
alpha2,3-sialyltransferase
beta-galactoside alpha-2,3-sialyltransferase 4
NP_991375.1
XP_005226874.1
XP_024842763.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205806.1 → NP_991375.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 precursor

    See identical proteins and their annotated locations for NP_991375.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ584673
    UniProtKB/TrEMBL
    A0A3Q1MGH3, F1MIZ3, Q70E76
    Conserved Domains (1) summary
    pfam00777
    Location:87 → 331
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    29698993..29739108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005226817.3 → XP_005226874.1  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform X2

    See identical proteins and their annotated locations for XP_005226874.1

    UniProtKB/TrEMBL
    A0A3Q1MGH3, F1MIZ3, Q70E76
    Related
    ENSBTAP00000073357.2, ENSBTAT00000075324.2
    Conserved Domains (1) summary
    pfam00777
    Location:87 → 331
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  2. XM_024986995.2 → XP_024842763.2  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1M6Q2, A0A3Q1MGH3
    Related
    ENSBTAP00000065690.2, ENSBTAT00000077201.2
Nucleotide Protein Strain
Heading Accession and Version

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