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aux - auxilin

Predicted to enable AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Involved in clathrin-dependent endocytosis; compound eye morphogenesis; and sperm individualization. Located in Golgi stack. Is expressed in several structures, including adult head; embryonic/larval garland cell; embryonic/larval midgut primordium; garland cell primordium; and salivary gland body primordium. Used to study Parkinson's disease and Parkinson's disease 19A. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 19A. Orthologous to several human genes including GAK (cyclin G associated kinase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa