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CG1103 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40547, updated on 4-Jan-2025

Summary

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Official Symbol
CG1103provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037235
Locus tag
Dmel_CG1103
See related
AllianceGenome:FB:FBgn0037235
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.152; Dmel\CG1103
Summary
Is expressed in several structures, including anterior endoderm; embryonic epipharynx; embryonic hypopharynx; endoderm anlage; and gut section. Human ortholog(s) of this gene implicated in Usher syndrome type 3A; autosomal recessive nonsyndromic deafness; and retinitis pigmentosa 61. Orthologous to human CLRN1 (clarin 1); CLRN2 (clarin 2); and CLRN3 (clarin 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG1103 in Genome Data Viewer
Location:
82A4-82A4; 3-47.1 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4337755..4339914)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (163477..165636)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene S-phase kinase-associated protein 2 Neighboring gene huckebein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Using Drosophila to study mechanisms of hereditary hearing loss. Li T, et al. Dis Model Mech, 2018 May 31. PMID 29853544, Free PMC Article
  2. Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants. Sun K, et al. PLoS Genet, 2012 Feb. PMID 22347817, Free PMC Article
  3. Adaptation to Chronic Nutritional Stress Leads to Reduced Dependence on Microbiota in Drosophila melanogaster. Erkosar B, et al. mBio, 2017 Oct 24. PMID 29066546, Free PMC Article
  4. Comparative exploration of mammalian deafness gene homologues in the Drosophila auditory organ shows genetic correlation between insect and vertebrate hearing. Sutton DC, et al. PLoS One, 2024. PMID 38412189, Free PMC Article
  5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1103-PA
CG1103-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    4337755..4339914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141199.4 → NP_649456.3  uncharacterized protein Dmel_CG1103, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649456.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q960K3, Q9VN09
    Related
    FBpp0078549
    Conserved Domains (1) summary
    pfam13903
    Location:22 → 203
    Claudin_2; PMP-22/EMP/MP20/Claudin tight junction

  2. NM_001043195.3 → NP_001036660.1  uncharacterized protein Dmel_CG1103, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036660.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q960K3, Q9VN09
    Conserved Domains (1) summary
    pfam13903
    Location:22 → 203
    Claudin_2; PMP-22/EMP/MP20/Claudin tight junction
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q960K3 Q960K3

Gene LinkOut

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