Sfxn1-3 Sideroflexin 1/3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Sfxn1-3provided by FlyBase
Official Full Name: Sideroflexin 1/3provided by FlyBase
Primary source: FLYBASE:FBgn0037239
Locus tag: Dmel_CG11739
See related: AllianceGenome:FB:FBgn0037239
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:Posey55; CG11739; Dmel\CG11739; Sfxn3
Summary: Enables L-serine transmembrane transporter activity. Involved in serine import into mitochondrion. Located in mitochondrion. Is expressed in adult head; adult heart; and spermatozoon. Orthologous to human SFXN1 (sideroflexin 1) and SFXN3 (sideroflexin 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (4378600..4381210)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (204322..206932)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
enables L-serine transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables monoatomic ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mitochondrial transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of one-carbon metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in serine import into mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in serine import into mitochondrion	IDA Inferred from Direct Assay more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

Names: CG11739-PA; CG11739-PB; CG11739-PC; CG11739-PD; Sfxn1-3-PA; Sfxn1-3-PB; Sfxn1-3-PC; Sfxn1-3-PD; sideroflexin

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The following sections contain reference sequences that belong to a specific genome build. Explain