sdr16c5a short chain dehydrogenase/reductase family 16C, member 5a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sdr16c5aprovided by ZNC
Official Full Name: short chain dehydrogenase/reductase family 16C, member 5aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2049
See related: Ensembl:ENSDARG00000016233 AllianceGenome:ZFIN:ZDB-GENE-040426-2049
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:76925
Summary: Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be active in lipid droplet. Orthologous to human SDR16C5 (short chain dehydrogenase/reductase family 16C member 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (11483072..11504349, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (11699473..11720750, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables all-trans-retinol dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in lipid droplet	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: short chain dehydrogenase/reductase family 16C, member 5a

NP_998043.2

EC 1.1.1.105

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_212878.2 → NP_998043.2 short chain dehydrogenase/reductase family 16C, member 5a

Status: VALIDATED

Source sequence(s)

EH548862, EH551860, EH566802

UniProtKB/TrEMBL

A0A8M1PI82, A8E7S3

Related

ENSDARP00000008564.6, ENSDART00000019392.7

Conserved Domains (2) summary

cd05339
Location:38 → 280

17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

pfam00106
Location:37 → 227

adh_short; short chain dehydrogenase