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atms antimeros [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40593, updated on 4-Jan-2025

Summary

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Official Symbol
atmsprovided by FlyBase
Official Full Name
antimerosprovided by FlyBase
Primary source
FLYBASE:FBgn0010750
Locus tag
Dmel_CG2503
See related
AllianceGenome:FB:FBgn0010750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0172774.113; anon-WO0172774.114; anon-WO0172774.116; Atms; CG2503; Dmel\CG2503; dPaf1; l(3)01456; l(3)02466; l(3)rK509; PAF; Paf1; PAF1
Summary
Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Involved in positive regulation of DNA-templated transcription. Located in euchromatin. Part of Cdc73/Paf1 complex. Is expressed in organism. Orthologous to human PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See atms in Genome Data Viewer
Location:
82D3-82D5; 3-47.1 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4750035..4777490)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (575757..603212)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR46137 Neighboring gene transforming acidic coiled-coil protein Neighboring gene mir-9384 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Coiled-coil domain containing protein 39

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Toxicity of pathogenic ataxin-2 in Drosophila shows dependence on a pure CAG repeat sequence. McGurk L, et al. Hum Mol Genet, 2021 Sep 15. PMID 34077532, Free PMC Article
  2. Drosophila Paf1 modulates chromatin structure at actively transcribed genes. Adelman K, et al. Mol Cell Biol, 2006 Jan. PMID 16354696, Free PMC Article
  3. Drosophila PAF1 Modulates PIWI/piRNA Silencing Capacity. Clark JP, et al. Curr Biol, 2017 Sep 11. PMID 28844648, Free PMC Article
  4. Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny. Buszczak M, et al. Science, 2009 Jan 9. PMID 19039105, Free PMC Article
  5. Gain of affinity point mutation in the serotonin receptor gene 5-HT2Dro accelerates germband extension movements during Drosophila gastrulation. Schaerlinger B, et al. Dev Dyn, 2007 Apr. PMID 17366631

See all (59) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: 4753299-4757535 mobile_element_type = transposon:F{}1209
  • Loc: 4759778-4761207 mobile_element_type = transposon:hopper{}1210

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA polymerase II complex binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Cdc73/Paf1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Cdc73/Paf1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Cdc73/Paf1 complex IEA
Inferred from Electronic Annotation
more info
  
located_in euchromatin IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
antimeros
Names
CG2503-PA
CG2503-PB
atms-PA
atms-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    4750035..4777490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275334.1 → NP_001262263.1  antimeros, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262263.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VN55
    Conserved Domains (1) summary
    pfam03985
    Location:27 → 414
    Paf1; Paf1

  2. NM_141236.3 → NP_649493.1  antimeros, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649493.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VN55
    Related
    FBpp0078508
    Conserved Domains (1) summary
    pfam03985
    Location:27 → 414
    Paf1; Paf1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VN55 Q9VN55

Gene LinkOut

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