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Nmdar1 - NMDA receptor 1

Contributes to NMDA glutamate receptor activity. Involved in several processes, including behavioral response to ethanol; learning or memory; and sensory perception of touch. Located in postsynaptic membrane. Part of NMDA selective glutamate receptor complex. Is expressed in several structures, including adult head; brain; larval central nervous system; synaptic neuropil domain; and synaptic neuropil subdomain. Human ortholog(s) of this gene implicated in alcohol use disorder; autosomal dominant intellectual developmental disorder 8; cerebral infarction; and developmental and epileptic encephalopathy 101. Orthologous to human GRIN1 (glutamate ionotropic receptor NMDA type subunit 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa