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CRMP - Collapsin Response Mediator Protein

Enables dihydropyrimidinase activity. Involved in several processes, including 'de novo' pyrimidine nucleobase biosynthetic process; Ras protein signal transduction; and centrosome localization. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including adult head; embryonic head sensory system; ganglia; larval central nervous system; and sensory nervous system primordium. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome; dihydropyrimidinase deficiency; and purine-pyrimidine metabolic disorder. Orthologous to several human genes including CRMP1 (collapsin response mediator protein 1); DPYSL3 (dihydropyrimidinase like 3); and DPYSL5 (dihydropyrimidinase like 5). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to CRMP

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Species Gene Architecture aa