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Dcps Decapping enzyme, scavenger [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40711, updated on 4-Jan-2025

Summary

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Official Symbol
Dcpsprovided by FlyBase
Official Full Name
Decapping enzyme, scavengerprovided by FlyBase
Primary source
FLYBASE:FBgn0037372
Locus tag
Dmel_CG2091
See related
AllianceGenome:FB:FBgn0037372
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2091; Dmel\CG2091
Summary
Predicted to enable 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity and RNA 7-methylguanosine cap binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to be active in P-body and nucleus. Is expressed in organism. Orthologous to human DCPS (decapping enzyme, scavenger). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Dcps in Genome Data Viewer
Location:
83C2-83C2; 3-47.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5753318..5754774, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1579040..1580496, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Symplekin Neighboring gene MLF1-adaptor molecule Neighboring gene Secretory 8 Neighboring gene uncharacterized protein Neighboring gene jagunal

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. Page AR, et al. EMBO J, 2005 Dec 21. PMID 16369566, Free PMC Article
  2. Patterns of gene expression during Drosophila mesoderm development. Furlong EE, et al. Science, 2001 Aug 31. PMID 11486054
  3. A systems biology analysis of the Drosophila phagosome. Stuart LM, et al. Nature, 2007 Jan 4. PMID 17151602
  4. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
  5. Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. Okada H, et al. Nat Commun, 2016 Sep 1. PMID 27582081, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA 7-methylguanosine cap binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
decapping enzyme, scavenger
Names
CG2091-PA
Dcps-PA
NP_649582.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    5753318..5754774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141325.3 → NP_649582.1  decapping enzyme, scavenger [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649582.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VNH5
    Related
    FBpp0078327
    Conserved Domains (3) summary
    COG5075
    Location:17 → 307
    COG5075; Uncharacterized conserved protein [Function unknown]
    pfam05652
    Location:15 → 124
    DcpS; Scavenger mRNA decapping enzyme (DcpS) N-terminal
    pfam11969
    Location:155 → 260
    DcpS_C; Scavenger mRNA decapping enzyme C-term binding
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VNH5 Q9VNH5

Gene LinkOut

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