U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SLC6A1 solute carrier family 6 member 1 [ Bos taurus (domestic cattle) ]

Gene ID: 407118, updated on 1-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
SLC6A1provided by VGNC
Official Full Name
solute carrier family 6 member 1provided by VGNC
Primary source
VGNC:VGNC:34913
See related
BGD:BT18844; Ensembl:ENSBTAG00000005857
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SLC6A1 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (55035897..55075940)

Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 11 Neighboring gene uncharacterized LOC132343470 Neighboring gene store-operated calcium entry-associated regulatory factor-like Neighboring gene histamine receptor H1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mutations in Rhipicephalus microplus GABA gated chloride channel gene associated with fipronil resistance. Castro Janer E, et al. Ticks Tick Borne Dis, 2019 Jun. PMID 30898542
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This is the first documentation of mutations in the GABA-Cl gene associated with fipronil-resistant in Rhipicephalus microplus.
    Title: Mutations in Rhipicephalus microplus GABA gated chloride channel gene associated with fipronil resistance.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables gamma-aminobutyric acid:sodium:chloride symporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neurotransmitter transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
sodium- and chloride-dependent GABA transporter 1
Names
GABA transporter GAT-1 homolog
solute carrier family 6 (neurotransmitter transporter, GABA), member 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001077836.1 → NP_001071304.1  sodium- and chloride-dependent GABA transporter 1

    See identical proteins and their annotated locations for NP_001071304.1

    Status: PROVISIONAL

    Source sequence(s)
    BC126623
    UniProtKB/TrEMBL
    A0AAF6DMF8, A0JND1, F1N315
    Related
    ENSBTAP00000007699.6, ENSBTAT00000007699.7
    Conserved Domains (1) summary
    cd11506
    Location:2 → 599
    SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    55035897..55075940
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024982413.2 → XP_024838181.1  sodium- and chloride-dependent GABA transporter 1 isoform X1

    UniProtKB/TrEMBL
    A0AAF6DMF8, A0JND1, F1N315
    Conserved Domains (1) summary
    cd11506
    Location:2 → 599
    SLC6sbd_GAT1; Na(+)- and Cl(-)-dependent GABA transporter 1; solute-binding domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.