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glob3 globin 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40726, updated on 4-Jan-2025

Summary

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Official Symbol
glob3provided by FlyBase
Official Full Name
globin 3provided by FlyBase
Primary source
FLYBASE:FBgn0037385
Locus tag
Dmel_CG14675
See related
AllianceGenome:FB:FBgn0037385
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14675; DmeGb3; Dmel\CG14675; Glob3; GLOB3
Summary
Predicted to enable heme binding activity and oxygen binding activity. Predicted to be located in cytoplasm. Is expressed in early elongation stage spermatid; onion stage spermatid; organism; primary spermatocyte; and secondary spermatocyte. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See glob3 in Genome Data Viewer
Location:
83C4-83C4; 3-47.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5830062..5831785)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1655784..1657507)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Secretory 20 Neighboring gene degringolade Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45192 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Divergent roles of the Drosophila melanogaster globins. Burmester T, et al. J Insect Physiol, 2018 Apr. PMID 28606854
  2. The Globin Gene Family in Arthropods: Evolution and Functional Diversity. Prothmann A, et al. Front Genet, 2020. PMID 32922435, Free PMC Article
  3. Testes-specific hemoglobins in Drosophila evolved by a combination of sub- and neofunctionalization after gene duplication. Gleixner E, et al. BMC Evol Biol, 2012 Mar 19. PMID 22429626, Free PMC Article
  4. The hemoglobin genes of Drosophila. Burmester T, et al. FEBS J, 2006 Feb. PMID 16420471
  5. Chronic low-dose γ-irradiation of Drosophila melanogaster larvae induces gene expression changes and enhances locomotive behavior. Kim CS, et al. J Radiat Res, 2015 May. PMID 25792464, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables heme binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen binding ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
globin 3
Names
CG14675-PA
glob3-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    5830062..5831785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141340.3 → NP_649597.3  globin 3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649597.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V5J0, Q9I7P6
    Conserved Domains (1) summary
    cd01040
    Location:44 → 169
    Mb_like; myoglobin_like; M family globin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I7P6 Q9I7P6

Gene LinkOut

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