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CG31559 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40749, updated on 9-Dec-2024

Summary

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Official Symbol
CG31559provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051559
Locus tag
Dmel_CG31559
See related
AllianceGenome:FB:FBgn0051559
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
31559; CG11461; CG15584; Dmel\CG31559
Summary
Predicted to be involved in sensory perception of sound. Is expressed in embryonic dorsal epidermis; embryonic head epidermis; embryonic hypopharynx; embryonic ventral epidermis; and gut section. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 25. Orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG31559 in Genome Data Viewer
Location:
83D5-83D5; 3-47.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6150116..6157235, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1975838..1982957, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43486 Neighboring gene long non-coding RNA:CR43487 Neighboring gene uncharacterized protein Neighboring gene Osiris 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Natural Genetic Variation Screen in Drosophila Identifies Wnt Signaling, Mitochondrial Metabolism, and Redox Homeostasis Genes as Modifiers of Apoptosis. Palu RAS, et al. G3 (Bethesda), 2019 Dec 3. PMID 31570502, Free PMC Article
  2. Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth. Hossain MS, et al. J Cell Biol, 2023 Sep 4. PMID 37389657, Free PMC Article
  3. dusky-like is required to maintain the integrity and planar cell polarity of hairs during the development of the Drosophila wing. Adler PN, et al. Dev Biol, 2013 Jul 1. PMID 23623898, Free PMC Article
  4. Trichomes on female reproductive tract: rapid diversification and underlying gene regulatory network in Drosophila suzukii and its related species. Tanaka KM, et al. BMC Ecol Evol, 2022 Jul 28. PMID 35902820, Free PMC Article
  5. Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster. Olivares GH, et al. Sleep, 2023 Apr 12. PMID 36718043

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in sensory perception of sound IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31559-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6150116..6157235 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169127.3 → NP_731045.1  uncharacterized protein Dmel_CG31559 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_731045.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8SZ66, Q9VNL4
    Related
    FBpp0078265
    Conserved Domains (1) summary
    cd03031
    Location:306 → 451
    GRX_GRX_like; Glutaredoxin (GRX) family, GRX-like domain containing protein subfamily; composed of uncharacterized eukaryotic proteins containing a GRX-like domain having only one conserved cysteine, aligning to the C-terminal cysteine of the CXXC motif of GRXs. This ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VNL4.2 Q9VNL4

Gene LinkOut

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