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Hr83 Hormone receptor 83 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40783, updated on 4-Jan-2025

Summary

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Official Symbol
Hr83provided by FlyBase
Official Full Name
Hormone receptor 83provided by FlyBase
Primary source
FLYBASE:FBgn0037436
Locus tag
Dmel_CG10296
See related
AllianceGenome:FB:FBgn0037436
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10296; DHR83; Dmel\CG10296; HR83; NR2E5
Summary
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Located in heterochromatin and nucleolus. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Hr83 in Genome Data Viewer
Location:
83E4-83E4; 3-47.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6349243..6350512)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2174965..2176234)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Small ribonucleoprotein particle protein SmD2 Neighboring gene uncharacterized protein Neighboring gene p21-activated kinase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DHR51, the Drosophila melanogaster homologue of the human photoreceptor cell-specific nuclear receptor, is a thiolate heme-binding protein. de Rosny E, et al. Biochemistry, 2008 Dec 16. PMID 19086271
  2. Dynamic regulation of Drosophila nuclear receptor activity in vivo. Palanker L, et al. Development, 2006 Sep. PMID 16914501, Free PMC Article
  3. Spatial profiling of nuclear receptor transcription patterns over the course of Drosophila development. Wilk R, et al. G3 (Bethesda), 2013 Jul 8. PMID 23665880, Free PMC Article
  4. The Drosophila FTZ-F1 nuclear receptor mediates juvenile hormone activation of E75A gene expression through an intracellular pathway. Dubrovsky EB, et al. J Biol Chem, 2011 Sep 23. PMID 21832074, Free PMC Article
  5. Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Maglich JM, et al. Genome Biol, 2001. PMID 11532213, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nuclear receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
hormone receptor 83
Names
CG10296-PA
Hr83-PA
drosophila hormone receptor 83

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6349243..6350512
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141390.1 → NP_649647.1  hormone receptor 83 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649647.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VI12
    Related
    FBpp0081210, FBtr0081713
    Conserved Domains (1) summary
    cd06957
    Location:7 → 88
    NR_DBD_PNR_like_2; DNA-binding domain of the photoreceptor cell-specific nuclear receptor (PNR) like is composed of two C4-type zinc fingers
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VI12 Q9VI12

Gene LinkOut

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