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glob2 globin 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40807, updated on 9-Dec-2024

Summary

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Official Symbol
glob2provided by FlyBase
Official Full Name
globin 2provided by FlyBase
Primary source
FLYBASE:FBgn0250846
Locus tag
Dmel_CG15180
See related
AllianceGenome:FB:FBgn0250846
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-SAGE:Wang-121; CG15180; DmeGb2; Dmel\CG15180; Glob2
Summary
Predicted to enable heme binding activity and oxygen binding activity. Predicted to be located in nucleus. Is expressed in early elongation stage spermatid; onion stage spermatid; organism; primary spermatocyte; and secondary spermatocyte. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See glob2 in Genome Data Viewer
Location:
83F4-83F4; 3-47.5 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6605997..6608914, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2431719..2434636, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene solwind

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Globin Gene Family in Arthropods: Evolution and Functional Diversity. Prothmann A, et al. Front Genet, 2020. PMID 32922435, Free PMC Article
  2. Testes-specific hemoglobins in Drosophila evolved by a combination of sub- and neofunctionalization after gene duplication. Gleixner E, et al. BMC Evol Biol, 2012 Mar 19. PMID 22429626, Free PMC Article
  3. Divergent roles of the Drosophila melanogaster globins. Burmester T, et al. J Insect Physiol, 2018 Apr. PMID 28606854
  4. The hemoglobin genes of Drosophila. Burmester T, et al. FEBS J, 2006 Feb. PMID 16420471
  5. Proteomic analysis of individual fruit fly hemolymph. Zeng Q, et al. J Chromatogr B Analyt Technol Biomed Life Sci, 2015 Feb 15. PMID 25596379

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables heme binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen binding ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
globin 2
Names
CG15180-PB
CG15180-PC
CG15180-PD
anon-SAGE:Wang-121
glob2-PB
glob2-PC
glob2-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    6605997..6608914 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275392.2 → NP_001262321.1  globin 2, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262321.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H8F4P7
    Conserved Domains (1) summary
    cd01040
    Location:61 → 161
    Mb_like; myoglobin_like; M family globin domain

  2. NM_001275393.1 → NP_001262322.1  globin 2, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262322.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KGM9
    Conserved Domains (1) summary
    cd01040
    Location:61 → 148
    Mb_like; myoglobin_like; M family globin domain

  3. NM_141412.3 → NP_649669.3  globin 2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649669.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V6L1, Q9VI36
    Conserved Domains (1) summary
    cd01040
    Location:61 → 161
    Mb_like; myoglobin_like; M family globin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KGM9 A0A0B4KGM9
H8F4P7 H8F4P7
Q4V6L1 Q4V6L1

Gene LinkOut

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