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agt - O-6-alkylguanine-DNA alkyltransferase

Enables methylated-DNA-[protein]-cysteine S-methyltransferase activity. Involved in DNA alkylation repair. Is expressed in organism and wing disc. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endocrine gland cancer (multiple); granulosa cell tumor; high grade glioma (multiple); and retinoblastoma. Orthologous to human MGMT (O-6-methylguanine-DNA methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to agt

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Species Gene Architecture aa