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Sodh1 - Sorbitol dehydrogenase 1

Enables L-iditol 2-dehydrogenase (NAD+) activity. Involved in fructose biosynthetic process and sorbitol catabolic process. Predicted to be active in cytosol. Is expressed in several structures, including adult head; adult heart; amnioserosa; dorsal ectoderm anlage; and ectoderm anlage. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy 8. Orthologous to human SORD (sorbitol dehydrogenase). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa