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CG1965 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 40842, updated on 9-Dec-2024

Summary

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Official Symbol
CG1965provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037466
Locus tag
Dmel_CG1965
See related
AllianceGenome:FB:FBgn0037466
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1965
Summary
Predicted to enable DNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Orthologous to several human genes including PAXBP1 (PAX3 and PAX7 binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG1965 in Genome Data Viewer
Location:
84B2-84B2; 3-48 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (7067401..7071624)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2893123..2897346)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene don juan like Neighboring gene Male-specific transcript 84B Neighboring gene uncharacterized protein Neighboring gene UFM1 specific ligase 1 Neighboring gene antisense RNA:CR45908 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Nutrient-Responsive Molecular Chaperone Hsp90 Supports Growth and Development in Drosophila. Ohhara Y, et al. Front Physiol, 2021. PMID 34239451, Free PMC Article
  2. Lack of the Drosophila BEAF insulator proteins alters regulation of genes in the Antennapedia complex. Roy S, et al. Mol Genet Genomics, 2011 Feb. PMID 21132442
  3. The Wright stuff: reimagining path analysis reveals novel components of the sex determination hierarchy in Drosophila melanogaster. Fear JM, et al. BMC Syst Biol, 2015 Sep 4. PMID 26335107, Free PMC Article
  4. Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Beckstead RB, et al. Insect Biochem Mol Biol, 2007 Jun. PMID 17517334, Free PMC Article
  5. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
involved_in spliceosomal complex disassembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of U2-type post-mRNA release spliceosomal complex IEA
Inferred from Electronic Annotation
more info
  
part_of catalytic step 2 spliceosome HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of precatalytic spliceosome HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG1965-PA
CG1965-PB
CG1965-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    7067401..7071624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275396.1 → NP_001262325.1  uncharacterized protein Dmel_CG1965, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262325.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KF71
    Conserved Domains (1) summary
    PRK06647
    Location:11 → 89
    PRK06647; DNA polymerase III subunits gamma and tau; Validated

  2. NM_001260027.2 → NP_001246956.1  uncharacterized protein Dmel_CG1965, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246956.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K6A9
    Conserved Domains (1) summary
    PRK06647
    Location:11 → 89
    PRK06647; DNA polymerase III subunits gamma and tau; Validated

  3. NM_141432.3 → NP_649689.1  uncharacterized protein Dmel_CG1965, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649689.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VI54
    Related
    FBpp0081148
    Conserved Domains (1) summary
    pfam07842
    Location:619 → 829
    GCFC; GC-rich sequence DNA-binding factor-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K6A9 A0A0B4K6A9
A0A0B4KF71 A0A0B4KF71
Q8MRQ8 Q8MRQ8
Q9VI54 Q9VI54

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